Dados do Trabalho

Título

Translation, Cross‑Cultural Adaptation, and Validation to Brazilian Portuguese of the Cerebellar Cognitive Afective/Schmahmann Syndrome Scale

Resumo

INTRODUCTION The Cerebellar Cognitive Afective Syndrome (CCAS) is characterized by defcits in executive functions, language processing, spatial orientation, and afect regulation in patients with cerebellar disease. The symptoms can occur isolated or along with motor and coordination symptoms. OBJECTIVES The aim of our study was to translate and culturally adapt the CCAS scale to Brazilian Portuguese and validate the scale in our population. METHODS We performed a cross-sectional study with patients with primary and secondary ataxia. The study included 111 individuals, aged between 20 and 80 years, of both genders, 20 without cognitive and/or afective complaints who participated in the pre-test phase, 40 with cerebellar disease (hereditary/neurodegenerative ataxia or acquired/secondary cerebellar ataxia), and 51 healthy controls with no evidence of cognitive impairment
and no afective symptoms matched for sex, age, and educational level. The scale was translated, culturally adapted, and validated. Statistical analysis of the data was performed, with association tests, mean comparison, and ROC curve analysis. RESULTS In the association test, the items Semantic Fluency (P= >0.999) and Phonemic Fluency (P= 0.386) did not present a statistically significant difference when comparing the group of patients to the control group. The scale’s internal reliability, assessed by Cronbach’s alpha, was 0.752, demonstrating a good degree of reliability and consistency between the scale’s subitems. Based on the analysis of the ROC Curve, optimal cutoff values were found for each subitem of the scale. CONCLUSION The translated and adapted scale has good internal consistency, is reproducible, has good reliability, and has the potential to be a reliable tool for screening cognitive symptoms in patients with cerebellar disease.

Palavras Chave

ATAXIA, COGNIÇÃO, AFETO