Dados do Trabalho

Título

Chronotype and hemodialysis-related social jet lag in chronic kidney disease patients

Resumo

INTRODUCTION: Chronodisruption refers to the chronic disruption of circadian rhythms leading to disease. Alterations of circadian rhythms have been observed in CKD patients and there is accumulating evidence that some of them may adversely affect health. Social jet lag is a term describing misalignment between social and biological times conventionally opposing work days to free days. CKD patients in hemodialysis are distributed into treatment shifts that configure a commitment that occurs three times a week. OBJECTIVE: The current study aimed to investigate if there is a hemodialysis-related social Jet Lag, to assess chronotype in hemodialysis patients and if there is inconsistency between the chronotype and the dialysis shift. METHODS: A total of 194 patients undergoing hemodialysis from three local dialysis units were enrolled from February to June 2022. Chronotype was estimated using Morning-Eveningness Questionnaire (MEQ) and a modified version of Munich Chronotype Questionnaire (MCQT) was used to estimate hemodialysis-related social Jet Lag. RESULTS: Hemodialysis related jet lag was 48.1 ± 1.4 min (range 0 – 4:57) and was inversely correlated to age (r=-0.216, p=0.01). Chronotype was distributed as 2.1% moderately evening, 31.4% intermediate, 39.2% moderately morning and 27.3% definitely morning. Forty-four patients (22.7%) were in morning shift treatment, 96 (49.5%) in afternoon shift and 54 (27.8%) in night shift treatment. Inconsistency between shift treatment and chronotype was detected in 38 (19.6%) and was related to higher MEQ scores (p<0.001). CONCLUSION: Therefore, this study seems to indicate that there may be a hemodialysis-related social jet lag, that morning chronotype is the most frequent in hemodialysis patients and higher score in MEQ is related to inconsistency between shift treatment and chronotype.

Palavras Chave

Chronotype; jet lag; hemodialysis