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Título

Restless Leg Syndrome/Willis-Ekbom disease (RLS/WED) and quality of life in hemodialysis patients

Resumo

INTRODUCTION: Chronic kidney disease (CKD) is associated with significant morbidity and mortality and can negatively impact on many aspects of health and wellbeing. Restless Leg Syndrome/Willis-Ekbom disease (RLS/WED) is one of the most common and unrecognized sleep disorders in CKD patients on hemodialysis and is associated to worse quality of life. OBJECTIVE: The current study aimed to investigate the prevalence of RLS/WED in patients undergoing hemodialysis, as well as the association with quality of life domains. METHODS: A total of 236 patients undergoing hemodialysis from three local dialysis units were enrolled from February to June 2022. RLS/WED was identified using a single screening question (‘When you try to relax in the evening or sleep at night, do you ever have unpleasant, restless feelings in your legs that can be relieved by walking or movement?’) and chronic persistent form was defined as symptoms at least twice a week. Quality of life was evaluated using the the Kidney Disease QoL Short Form (KDQOL-SF) by face-to-face interview. RESULTS: The prevalence of RLS/WED in hemodialysis patients was 30.1%. About 20.4% had chronic persistent form. Patients with RLS/WED, compared to non-RLS/WED patients, had significantly worse KDQOL-SF scores across multiple domains as sleep (p=0.003), quality of social interaction (p=0.02), cognitive function (p=0.001), burden of kidney disease (p=0.025), effects of kidney disease (p=0.01), symptoms (p=0.01), physical functioning (p=0.01), social function (p=0.04), and emotional role (0.02) CONCLUSION: Therefore, this study show that RLS/WED is a common disorder in hemodialysis patients and is related to worse perception of quality of life in several of its domains.

Palavras Chave

Restless Leg Syndrome; hemodialysis; quality of life; sleep.

Área

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