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Título

MORTALITY PROFILE OF PATIENTS WITH INFLAMMATORY POLYNEUROPATHY IN BRAZIL BETWEEN JANUARY 2010 AND DECEMBER 2020

Resumo

INTRODUCTION: Inflammatory polyneuropathy is clinically marked by progressive symptoms of weakness affecting the distal and proximal segments with consequent loss of functional capacity. In addition, these patients develop global loss of reflexes and sensitivity, especially vibratory and positional. Due to its autoimmune characteristic that generates an inflammatory response on the neurons, the treatment is performed with immunoglobulin, immunosuppression, and glucocorticoids, generating stability and even remission. However, as the disease progresses, the patient may develop respiratory failure, a major cause of death in this etiology even with therapeutic progress. OBJECTIVE: Describe the epidemiological profile of mortality for Inflammatory polyneuropathy. METHODOLOGY: This descriptive study was carried out using data from the Departamento de Informática do Sistema Único de Saúde (DATASUS), in which the Inflammatory Polyneuropathy mortality profile between January 2010 and December 2020 was evaluated. The mortality during this period was analyzed by education, age group, month of death, federation region, ethnicity, and gender. In the description of these categorical variables, their relative frequencies (%) will be calculated. Since this is a public domain database, submission to the Research Ethics Committee was not necessary. RESULTS: The total number of deaths in the 10-year period was 2283 individuals. There was a predominance of deaths in the school years between 8 and 11 years (22.56%), in the months of January (9.15%) and November (9.15%), in the age group between 60 and 69 years (20.59%), male (60.7%) and white (54%). CONCLUSIONS: There is a congruence of the mortality profile with the epidemiology of the disease. However, even with the treatment already established and the possibility of remission, the number of deaths from inflammatory polyneuropathy is still high. The higher incidence of mortality in patients with less education and older age suggest the lack of access to treatment as one of the causes for this fact. Thus, new studies are needed to solidify the literature about the motivations for maintaining high levels of deaths in an already well known disease.

Palavras Chave

INFLAMMATORY POLYNEUROPATHY; MORTALITY