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Título

REPORT OF MULTIPLE SCLEROSIS HOSPITALIZATIONS IN BRAZIL BETWEEN JANUARY 2010 AND DECEMBER 2020

Resumo

INTRODUCTION Multiple Sclerosis (MS) is the leading autoimmune, inflammatory, demyelinating, chronic disease of the central nervous system. MS affects about 2.3 million people worldwide and is the most common cause of nontraumatic disability in young adults. It can cause a progressive neurological dysfunction in this population, leading to significant functional and economic damage. The disease presents itself through outbreaks, which lead to frequent hospitalizations and consequent important socioeconomic implications. OBJECTIVE Describe the epidemiological profile of hospitalized patients for MS. METHODOLOGY A descriptive epidemiologic study was carried out with data collected from the Departamento de Informática do Sistema Único de Saúde (DATASUS) system, in which the report of hospital admissions for MS between January 2010 and December 2020 was evaluated. The hospitalizations were analyzed by age group, ethnicity, region, care scheme, gender, total value, and number of days of stay. Patient mortality rate, deaths and the predominant age group were also described. The average was calculated, along with the standard deviation (SD) to describe the continuous variables and the relative frequency for the categorical variables. Since this is a public domain database, submission to the Research Ethics Committee was not necessary. RESULTS There were 30,768 hospitalizations. Most were white (58.26%), women (69.7%), between 30 and 39y (29.6%) and in the southeast region of the country (64.98%). About the care regimen, 70.3% were ignored at hospital admission; however, there was no significant difference between public and private. The total value of hospitalizations in these 10 years was R$1,757,360.311 (SD: R$714,199.89), with the mean price per hospitalization being R$686.19 (SD: R$129.44). With the total number of deaths in this time frame being 328 individuals, the year with the highest incidence was 2019 (N:51), with an average of 27.5 patient deaths/year. The average mortality rate is 1.14% with a total of 0.92% over 10 years. The predominant age group in the deaths was 50-59 years (19.51%). CONCLUSIONS The data of patients hospitalized for MS match with the epidemiology for the disease itself. Over the years, the number of hospitalizations remained high, making MS a high-cost disease, both because it affects an active population and because of the total costs of hospitalizations due to its progressive characteristics and frequent outbreaks.

Palavras Chave

MULTIPLE SCLEROSIS; HOSPITALIZATIONS;

Área

Neuroimunologia