Dados do Trabalho

Título

BIOMARKERS OF BRAIN ELECTRICAL ACTIVITY IN INDIVIDUALS WITH AUTISTIC SPECTRUM DISORDER

Resumo

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder
characterized by neurological disorders, which includes communication deficit,
decreased social interaction, behavioral pattern, restricted and repetitive
activities and interests. The diagnosis of ASD is clinical and based on the
Diagnostic and Statistical Manual of Mental Disorders (DSM-5). This defines ASD
as the entities Asperger's Syndrome, Autistic Disorder and Generalized
Developmental Disorder not otherwise specified, which include Childhood
Disintegrative Disorder and Rett's Syndrome. Due to the difficult diagnosis,
numerous studies with electroencephalogram (EEG) exams in autistic individuals
have shown interesting results in the search for a biomarker of this condition. In
this work, carried out by analyzing the EEG record in autistic individuals (N = 22)
in comparison to the control group (N = 8), it was found that in the TEA group
there was a lower oscillation power of the low frequency waves (alpha , delta and
theta) in relation to the control group, and in alpha and theta this finding occurred
in the whole brain. Along with this, there was a slight predominance of the gamma
oscillation power in the TEA group in relation to the healthy group, another fact
was the inverse relationship between the oscillation power of the low frequency
waves (alpha, theta and delta) and the power of range oscillation.