Dados do Trabalho

Título

Application of the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire in patients with narcolepsy

Resumo

Introduction: REM sleep behavior disorder is characterized by the loss of muscle atony during REM sleep associated with abnormal behaviors, often with dream enactments, which can even cause bodily harm to the patient and their bed partner. . It is considered a REM sleep parasomnia and can be idiopathic or associated with other diseases, including narcolepsy. When associated with narcolepsy, it usually presents an earlier onset and milder symptoms than when it is associated with other diseases, often going unnoticed by patients and health professionals.
Objective: To evaluate signs and symptoms of REM sleep behavior disorder in patients with narcolepsy through the application of a questionnaire.
Methodology: In the study, the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire was applied to patients with type 1 (N1) and type 2 (N2) narcolepsy. All patients evaluated had excessive daytime sleepiness and had a previous diagnosis of the disease through polysomnography and the multiple sleep latency test. Subjects were classified into N1 and N2 according to the result of the cerebrospinal fluid hypocretin dosage, which was performed in all patients studied.
Results: 71 adult individuals were evaluated, 45 of whom had N1 and 26 had N2. The score considered positive for the questionnaire was = or > 5. The mean score was 8.276 (SD: 2.801) in patients with N1 and 6.368 (SD: 4.669) in patients with N2. It was observed that there was a higher score on the questionnaire in patients with lower levels of hypocretin, and in the N1 group, the score result was significantly positive (p=0.00331).
Conclusion: It was observed that patients with narcolepsy have high scores when responding to the Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire. Despite being a known comorbidity in people with narcolepsy, this research shows the symptoms of REM sleep behavior disorder are more important than usually considered in clinical practice.

Palavras Chave

REM sleep behavior disorder, Narcolepsy, questionnaire