Dados do Trabalho


Título

EPIDEMIOLOGICAL PROFILE OF ACUTE FLACID PARALYSIS IN BRAZIL: 2015-2020

Resumo

Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy, currently considered the most frequent cause of acute flaccid paralysis (AFP) in children, after the eradication of poliomyelitis in developed countries. It is characterized by acute paralysis with areflexia and albuminocytological dissociation in the CSF, being a neurological emergency. The differential diagnosis of GBS offers a wide range of possibilities, among them spinal canal compression, transverse myelitis, botulism and cerebellar ataxia ¹. OBJECTIVE: To characterize the epidemiological profile of cases notified in Brazil of acute flaccid paralysis. METHODS: The data were extracted from the Notifiable Diseases Information System (SINAN) and encompassed the period from 2015 to 2020. RESULTS: Between 2015 and 2020, 2711 patients with AFP were notified in Brazil, and 2018 had the higher number of notifications (520/ 19.18%). The Northeast region showed the highest number of cases (1047/38.62%) and the Midwest was the region with the lowest cases of AFP (171/6.3%). As for age, 122 (4.5%) were under 1 year old, 966 (35.63%) were between 1 and 4 years, 805 were between 5 and 9 years and 818 were between 10 and 14 years. None patient over fifteen years was notified. In relation to gender, the male gender had the highest prevalence with 1545 cases (56.99%). The Brown color/race exceeded the other races. None cases were classified as "Corfirmed Wild Polivirus". CONCLUSION: It was found that AFP still occurs frequently in Brazil, especially in regions with lower socioeconomic status, in male children and in brown people. There were no reported cases of poliovirus.

Palavras Chave

Acute Flaccid Palsy, Epidemiological Monitoring, Neuroepidemiology

Área

Neuroepidemiologia

Autores

Eduardo Mariano Carvalho Silva, Jhonata Gabriel Moura Silva , Ana Carolina Nascimento de Sousa , Arthur Costa Junger, Fábio Pereira da Silva Júnior, João Victor Cunha Silva, Lays Saraiva Rodrigues Carvalho, Lorena Silva Viana, Luiz Felipe Bezerra de Sousa, Nínivi Daniely Farias Santos