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Título

COMPARATIVE ANALYSIS OF THE PROFILE OF HOSPITALIZATIONS AND DEATHS FROM MULTIPLE SCLEROSIS IN THE PRE AND INTRA PANDEMIC PERIOD IN BRAZIL

Resumo

Introduction: Multiple Sclerosis (MS) is the most prevalent chronic inflammatory disease of the CNS, and those with the disease require periodic specialized follow-up. The COVID-19 pandemic has had an impact on this population on access to health care and the outcome of the disease. Objective: Comparatively describe the profile of hospitalizations and deaths related to MS in Brazil in the pre (Apr/2019-Jan/2020) and intra (Feb/2020-Nov/2020) pandemic period by COVID-19. Methods: Descriptive and retrospective study carried out from DataSUS between Apr/19 and Nov/20. The variables analyzed were number of hospitalizations, age range, character of care, gender, race/color, and deaths. Results: In pre-pandemic, with a total of 3,864 hospitalizations, there was a peak in Jan/20 (518) and the lowest value in Dec/19 (208). Of 1551 in capital cities, 1074 occurred in São Paulo. 30-39 years old led with 1180 cases and 5-9 years was the lowest (4). There were 1872 urgent and 1992 elective admissions. There were 1286 male and 2578 female hospitalizations (2.004:1). By color/race, there were 2374 white and 895 brown people. There were 41 deaths in the country, 7 in capitals. The 50-59 age group led (13 deaths). 25 deaths occurred in men and 16 in women (1.56:1). By color/race, 22 deaths were in whites and 12 in browns. In intra-pandemic, with a total of 3105 hospitalizations (19.64% less), there was a peak in Apr/20 (498). Of 1272 in capitals, 815 occurred in São Paulo. 30-39 years old led with 947 cases and 5-9 years was the lowest (2). There were 1640 urgent admissions (12.39% less) and 1465 electives (26.45% less). In Apr/20 (498 hospitalizations), 350 were elective (70.29 %). On Sep/20, of the 190 hospitalizations, 170 were urgent (89.47%). There were 1003 men and 2102 women notified (2.09:1). By color/race, there were 1933 white and 724 brown people. There were 21 deaths in the country (48.78% less), 5 in capital cities. 40-49 and 50-59 years old presented 5 deaths each. 8 deaths occurred in men and 13 in women (1.625:1). By color/race, there were 11 deaths in whites and 7 in browns. Conclusion: White women aged 30-39 form the population most affected by MS in Brazil in the pre-pandemic period, while in deaths, white men aged 50-59. In the intra-pandemic period, there was a reduction in hospitalizations, but the epidemiologic profile regarding sex, race, and age remained the same. In deaths, however, white women aged 40-59 were the most affected.

Palavras Chave

COVID-19; Multiple Sclerosis; Immunology