Dados do Trabalho

Título

ALCOHOL AS A RISK FACTOR FOR DEMENTIA SYNDROMES

Resumo

Introduction: Alcoholism is a chronic disorder characterized by long periods of abstinence associated with periods of alcohol consumption relapses. It is already known that exposure to excess alcoholic beverages for a long period will lead to brain damage, such as reduced concentration, recent memory and can lead to pathologies such as dementia. Dementia is a persistent cognitive syndrome, with decreased functionality and changes in at least two cognitive domains. Under this question, many studies have done analyzes on the effects of chronic alcohol use and the brain damage that may be related. Because of these studies, several pathways for this damage have been suggested, including the neurotoxic effects of thiamine, ethanol, and acetaldehyde deficiency. Objetivo: Avaliar a relação entre o consumo inadequado de álcool e sua relação com a progressão das Síndromes Demências, investigando a quantidade e os limites entre o benefício e o dano no consumo de álcool. Methodology: This is a systematic literature review based on data extraction in indexes such as PUBMED and MEDLINE. Publications between 2018 and 2022 were considered, in the English language and with the following descriptors: Alcohol, Dementia, Neurology. Results: The beginning of the discussion about the positive or negative effects of alcohol is based on the lack of basic guidelines on the amount and frequency of alcohol intake that would be adequate to guarantee health benefits or harm. To fill this gap, the research cites important points about the levels of alcohol consumption, and indicates that light to moderate consumption of alcohol does not imply a high risk for causes of dementia, however when this intake goes to a high level, the risks of dementia have already been shown to be significantly higher. 8 drinks per week for women and 15 drinks per week for men is found to be significantly associated with a consistently high trajectory of cognitive function and a lower rate of cognitive decline. Conclusion: Notably, the relationship between alcohol and progression of dementia syndromes is related to the level of ethanol intake, in which low to moderate intakes present a lower risk for progression of brain damage than people with high alcohol intakes.

Palavras Chave

Alcohol. Dementia. neurology