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Título

EPIDEMIOLOGICAL PROFILE OF ACUTE FLACID PARALYSIS IN BRAZIL: 2015-2020

Resumo

INTRODUCTION: Guillain-Barré syndrome (GBS) is a acute inflammatory polyneuropathy, currently considered the most frequent cause of acute flaccid paralysis (AFP) in children after polio eradication in developed countries. It is characterized by acute paralysis with arreflexia and liquor albuminocytological dissociation, being it a neurological emergency. The differential diagnosis of GBS offers a wide range of possibilities, among them stands out spinal canal compression, transverse myelitis, botulism and cerebellar ataxia¹. OBJECTIVE: To characterize the epidemiological cases profile of notified acute flaccid paralysis between in Brazil 2015 and 2020. METHODS: The data were extracted from Notifiable Diseases Information System (SINAN) and encompassed the period from 2015 to 2020. RESULTS: Between 2015 and 2020, 2711 patients with AFP were notified in Brazil, and 2018 had the higher number of notifications (520/19.18%). The Northeast region showed the highest number of cases (1047/38.62%) and the Midwest was the region with the lowest cases of AFP (171/6.3%). As for age, 122 (4.5%) were under 1 year old, 966 (35.63%) were between 1 and 4 years, 805 were between 5 and 9 years and 818 were between 10 and 14 years. No patients over fifteen years was notified. In relation to gender, the male gender had the highest prevalence with 1545 cases (56.99%). The Brown color/race exceeded the other races. None cases were classified as "Corfirmed Wild Polivirus". CONCLUSION: It was found that AFP still occurs frequently in Brazil, especially in areas with lower socioeconomic status, in male children and in black race people. There was no poliovirus cases detected.

Palavras Chave

Acute Flaccid Paralysis, Epidemiological Monitoring, Neuroepidemiology