Dados do Trabalho

Título

Headache at the chronic stage of cerebral venous thrombosis

Resumo

Introduction: Headache is the most frequent symptom of cerebral venous thrombosis (CVT) but there is limited information about the frequency and phenotype of headache, weeks to months after CVT (post-CVT headache, PCH).
Objective: To assess the frequency, characteristics and predictors of PCH.
Methods: In this cross-sectional study, the frequency and characteristics of PCH were assessed in CVT survivors. Patients were interviewed between 6 months and 5 years after the CVT diagnosis. Clinical and imaging characteristics at the time of CVT diagnosis, as well as history of headache prior to CVT were compared in subjects with (GroupPCH) and without PCH (Groupcontrol).
Results: Subjects (n=100; 82% women) were assessed, on average, at 1.1 ± 1.6 years of follow-up. PCH was present in 59% of the patients, had phenotypes of tension-type-like headache in 31/59 (52.6%) and of migraine-like headache, in 16/59 (27.1%). History of primary headache prior to CVT was significantly more common (OR: 6.4; 95% CI: 1.7-36.3) in GroupPCH (33.9%) than in Groupcontrol (7.3%).
Conclusion: PCH was present in more than half of the patients. History of prior headache may be a risk factor for PCH. Prospective studies are required to confirm these findings and determine mechanisms, as well as interventions for prevention and treatment of PCH.

Palavras Chave

cerebral venous thrombosis, primary headache, chronic headache, secondary headache