Dados do Trabalho

Título

Unusual microbleeds critical illness brain MRI of Covid-19 patient

RESUMO

Covid-19, initially described as a respiratory system’s infection, is currently more and more recognized as a multiorganic disease, including neurological manifestations. We are reporting the imaging findings of the rare entity of critical illness-associated cerebral microbleeds in a COVID-19 45 years old woman with hypoxic respiratory failure, who was eventually intubated and ventilated, prolonged coma. She was tested positive for COVID-19 confirmed by reverse transcriptase polymerase chain reaction. The purpose of this study is to describe findings, in the form of cerebral microbleeds affecting different brain structures, observed in MRIs of critically ill patients. Multiple scattered cerebral microhaemorrhages diffusely distributed in the juxtacortical white matter and internal capsule region, sparing the deep and periventricular white matter, basal ganglia, thalami and cortex were seen. Cerebral microbleeds and leukoencephalopathy have been described in COVID-19 patients; although the mechanism remains unknown, possibilities include endotheliitis with thrombotic microangiopathy, excessive inflammation, prolonged respiratory failure, and hypoxemia.

Palavras Chave

COVID-19, microblees, critical care, coma