Program

Hope on the horizon? Exploring PACAP's role in migraine

08:30 - 08:45

Unveiling PACAP's role in migraine: Evidence from human provocation studies

08:45 - 09:00

Decoding PACAP signalling: Splice variants, pathways, and designer drugs

09:00 - 09:15

Can PACAP activate meningeal nociceptors?

09:15 - 09:30

PACAP vs. CGRP: Unveiling migraine mechanisms through mouse models

Decoding treatment success: unveiling biomarkers for migraine treatment

09:30 - 09:45

Profiling non-responders and super-responders to anti-CGRP treatment

09:45 - 10:00

Clinical features and biomarkers predicting treatment response in migraine

10:00 - 10:15

Role of central sensitisation and interictal allodynia

10:15 - 10:30

Molecular biomarkers and migraine treatment response

Break

Opening Ceremony and Presidential Symposium

IHS Special Lecture

Break

Artificial Intelligence: Regulation and monitory algorithm that reduces risk?

09:00 - 09:17

Connecting emotions, brain, and behaviour with wearables in migraine and chronic pain patients

09:17 - 09:34

Patient data to give the right patient the right treatment at the right time

09:34 - 09:51

The implementation of AI in the migraine field – from neural networks to networked care

09:51 - 10:00

Discussion

– Migraine-related cognitive functions – real or not real: Evidence and description, pathophysiology, implications of treatment

10:00 - 10:15

Deciphering the mechanisms: Pathophysiology of migraine-related cognitive dysfunction

10:15 - 10:30

Cognitive impairments in primary and secondary headache disorders

10:30 - 10:45

Migraine and cognitive decline

10:45 - 11:00

Altered cognition-related brain activity and interactions with acute pain

Break

IHS Annual General Meeting and Advisory Council

Sex role in response to acute and preventive treatment of migraine: Is the evidence strong enough to exclude males?

15:00 - 15:15

Sex differences in response to triptans

15:15 - 15:30

Pain behaviours to CGRP and other neuropeptides – sex differences?

15:30 - 15:45

Evaluation of outcomes of CGRP-targeting therapies for acute and preventive migraine treatment based on patient sex

15:45 - 16:00

Is there a gender difference in the response to onabotulinumtoxinA or CGRP inhibitors in chronic migraine?

Break

Unraveling the Impact of Headaches on the Transition from Acute to Chronic Orofacial Pain

Do genetic variants determine endophenotypes and comorbidities of migraine?

13:00 - 13:15

Rare variants with large effects provide functional insights into the pathology of migraine subtype

13:15 - 13:30

Shared genetics and causal relationships between migraine and its comorbidities

13:30 - 13:45

Genetic susceptibility of migraine endophenotypes across ethnicities

13:45 - 14:00

Mapping out neurons that contribute to headache (USA)

Primary care approach to headache patients

14:00 - 14:15

Migraine multidisciplinary approach in family medicine

14:15 - 14:30

Exclusion of important life-threatening causes of headache

14:30 - 14:45

Managing primary headache disorders in a primary headache care setting

14:45 - 15:00

Discussion

The complex relationship between circadian rhythm and cluster headache

16:15 - 16:30

Circadian features of headache disorders – can I explain why?

16:30 - 16:45

Genetics and chronobiology of cluster headache

16:45 - 17:00

Chronobiology of cluster headache attacks – my proposed explanation

17:00 - 17:15

Discussion

Facial representation of primary headache

13:00 - 13:15

Facial trigeminal autonomic cephalalgias (TACs)

13:15 - 13:30

Low face migraine

13:30 - 13:45

Facial tension type headache

13:45 - 14:00

Optimising combined treatment for migraine and temporomandibular disease.

Is migraine with aura a distinct disorder or a symptom of migraine?

14:00 - 14:15

Migraine with and without aura are distinct disorders

14:15 - 14:30

CSD provides a common therapeutic target for widely prescribed migraine prophylactic drugs and neuromodulation devices

14:30 - 14:45

Brain imaging in migraine with and without aura: Similarities and differences

14:45 - 15:00

Discussion

Global, regional, and national epidemiology and burden of headache: Unravelling the past and envisioning the future

16:15 - 16:30

Global disparities in migraine care: A call for universal access to diagnosis and treatment

16:30 - 16:45

Regional variations in headache burden

16:45 - 17:00

What did I learn from the field in LMIC? What did I bring from the metropolis to the field?

17:00 - 17:15

Discussion

What can headaches in children and adolescents teach us about caring for adults?

13:00 - 13:15

The biology and genetics of childhood and adolescent migraine: Why the prevalence is similar in childhood but different in adolescence

13:15 - 13:30

Mitochondrial role in paediatric migraine pathophysiology

13:30 - 13:45

The role of sex hormones in migraine attack initiation: Can we explain onset of migraine attacks during puberty?

13:45 - 14:00

Impact of co-morbidity, resilience, and vulnerability on childhood and adolescent headaches

Is early treatment important in the approach to episodic and chronic migraine?

14:00 - 14:15

Treating the attack during the prodromal phase: Gain or waste?

14:15 - 14:30

Early prevention: Disease prevention or prevention of disease progression?

14:30 - 14:45

What do the guidelines say?

14:45 - 15:00

Discussion

Navigating the intersections: Headaches, epilepsy, and shared pathways

16:15 - 16:30

Migraine – a borderland disease to epilepsy: Near it but not of it

16:30 - 16:45

Pathophysiology of ictal and post-ictal headache

16:45 - 17:00

Migraine and idiopathic epilepsies comorbidity

17:00 - 17:15

Migraine and epilepsy: From bench to bedside

IHS grants 1

Deciphering idiopathic intracranial pressure: Is it a spinal fluid regulation disorder or a metabolic disease causing dysregulation of spinal fluid production?

14:00 - 14:15

Metabolic perspectives in idiopathic intracranial hypertension

14:15 - 14:30

Novel therapeutic approaches and efficacy of epidural blood patching or surgery in spontaneous intracranial hypotension

14:30 - 14:45

Proposing management strategies tailored to addressing intracranial hypotension

14:45 - 15:00

Discussion

Where does combining acute and preventive treatment fit?

16:15 - 16:30

Scientific rationale for polytherapy

16:30 - 16:45

Acute treatment of migraine: When one drug is not enough

16:45 - 17:00

Prophylactic treatment of migraine: When one drug is not enough

17:00 - 17:15

Experiences with dual therapy with onabotulinumtoxinA and CGRP antibodies: Real world evidence data

Cephalalgia Award Lecture

Controversies in migraine: The prodromal phase

17:00 - 17:15

Cracking the code: Inconsistencies and issues in assessing the migraine prodrome

17:15 - 17:30

Different kinds of migraine triggers are reported in different parts of the world

17:30 - 17:45

The hypothalamus: Conductor of the migraine prodrome

17:45 - 18:00

Is the hypothalamus to blame? Rethinking its role in the migraine prodrome

Trainees Tournament

Cluster headache and insights for the role of anti-CGRPs in acute and prophylactic treatment

09:00 - 09:15

Understanding the pathogenesis of cluster headache in the CGRP era: Where are we?

09:15 - 09:30

Do pathophysiological differences exist between episodic and chronic cluster headache?

09:30 - 09:45

Clinical response prediction of approved anti-CGRP in the prevention of cluster headache and what is next

09:45 - 10:00

Discussion

Break

Oral communications 1

Parallels and divergences in visual snow syndrome (VSS) and migraine

14:30 - 14:45

VSS is a form of migraine aura–overlapping clinical features, neurophysiology, and neuroimaging

14:45 - 15:00

VSS is a distinct clinical entity: What we learned from neuro-ophthalmological and behavioural research

15:00 - 15:15

Visual snow vs. migraine aura

15:15 - 15:30

Debate summary and novel insights into the syndrome

Break

Late-Breaking Abstracts (Basic)

- Migraine aura – a not-so-easy-to-detect condition

09:00 - 09:15

Decoding the aura table: Unveiling visual disturbances and perception in migraine auras

09:15 - 09:30

Beyond the scan: Exploring neuroimaging and the quest for objective documentation of migraine aura phenomena

09:30 - 09:45

Initiation and propagation of spreading depolarisation: Considerations for migraine

09:45 - 10:00

Discussion

Break

Oral Communications 2

Migraine in pregnancy and lactation

14:30 - 14:45

Sex and hormonal influences on migraine pain – the science

14:45 - 15:00

Prescribing for pregnancy: Managing chronic headache and migraine

15:00 - 15:15

CGRP, onabotulinumtoxinA, and others. Are they safe?

15:15 - 15:30

Addressing migraine in the breastfeeding period: Practical approaches for primary care providers

Break

Late-Breaking Abstracts (Clinical)

Migraine treatment in children and adolescents: Should we rewrite our guidelines?

09:00 - 09:15

Update on pharmacological options currently available for the treatment of migraine in children and adolescents

09:15 - 09:30

Does controlling migraine improve interictal cognition in children and adolescents? Does more need to be done?

09:30 - 09:45

What are the key messages for the non-pharmacological approach of migraine in children and adolescents?

09:45 - 10:00

Discussion

Break

Oral Communications 3

The surgeon's role in managing trigeminal neuropathic pain

14:30 - 14:45

Demystifying trigeminal neuropathic pain in the face and mouth - guidelines on diagnosis, treatment, and follow-up care

14:45 - 15:00

The science behind neuromodulation procedures for trigeminal neuralgia

15:00 - 15:10

The role of tumours in headaches and neuralgias – the perspective from neurosurgery

15:10 - 15:30

Discussion

Break

Late-Breaking Industry Abstracts

Update on neuromodulation

09:00 - 09:15

Transcranial direct current stimulation (tDCS)

09:15 - 09:30

Transcranial magnetic stimulation (TMS)

09:30 - 09:45

Peripheral nerve stimulation

09:45 - 10:00

Discussion

Break

IHS grants 2

Break

Headache management in low- and middle-income countries (LMIC): realities, challenges & solutions

14:30 - 14:45

Telemedicine as a solution for headaches in LMIC countries

14:45 - 15:00

Telemedicine in headache education

15:00 - 15:15

Partnership, education and care to improve the management of headaches in sub-Saharan Africa

15:15 - 15:30

Community Pharmacists in Headache Management: Expanding the Scope

15:30 - 15:45

Discussion

Break

Update on neurotoxins

16:00 - 16:20

Non-paralytic botulinum toxins for the treatment of headaches and pain

16:20 - 16:40

Anti-nociceptive activities of novel long-acting SNARE-inactivating biotherapeutics

16:40 - 17:00

Chimeric toxin-based therapeutics