Dados do Trabalho

Título

ALCOHOL AS A RISK FACTOR FOR LIP, ORAL CAVITY AND OROPHARYNX NEOPLASM: AN ANALYSIS OF THE EPIDEMIOLOGIC PROFILE OF THESES NEOPLASIA IN BRAZIL FROM 2008 TO 2021.

Introdução

Lip, oral cavity and oropharynx neoplasm are malign lesions that strikes from lips to posterior pharynx wall. Highly detectable by oral care follow up, up to 90% of the cases are squamous cells carcinoma. This neoplasm is unleashed by the accumulation of risk factors, being alcohol, together with tobacco and HPV, one of the main risk factors. The influence caused by it, can be explained by the action of its metabolite, acetaldehyde, over cell DNA chains and its increasing effect over other carcinogenic agents.

Objetivo

to analyse the relation between the taxes of hospitalization by lip, oral cavity and oropharynx neoplasm per 100 thousand habitants in the Brazilian states from January, 2008 to April, 2021 and the percentage of people who uses alcohol one or more times a week, according to the data from the 2019 National Health Research (PNS).

Método

The former study was done according to the transversal epidemiologic study model, the data was collected in the DATASUS database, and the National Health Research 2019 from the Brazilian Statistic Institute database. The data were tabulated in the program Microsoft Excel 2016, where were calculated the taxes and the values of the linear regression (Pearson correlation coefficient and p value).

Resultado

In the period from January, 2008, to April, 2021 there were 347,558 hospitalizations by lip, oral cavity and oropharynx cancer in Brazil. From these, more than 70% of the hospitalizations belonged to male sex (n= 248,959) while the female sex had 98,599 cases. Relating it to the age groups, there was a higher incidence in the ages between 50 and 59, followed by 60 to 69 and 40 to 49, respectively. The linear regression test revealed a significant positive correlation between the percentage of users of alcohol at least one time a week and the lip, oral cavity and oropharynx cancer tax (r=0.45 and p=0.018).

Conclusão

The former study found a relation between the consumption of alcoholic drinks and the taxes of hospitalization by mouth and oropharynx neoplasm. This relation, already well known by literature, remembers the importance of the fight against alcoholism as a way to prevent these cancers.

Palavras-chave

Alcoholism; Head and Neck Neoplasms ; Epidemiology.