Dados do Trabalho

Título

CLINICAL AND EPIDEMIOLOGICAL STUDY OF ONCOLOGY PATIENTS WITH COVID-19 IN A BRAZILIAN CAPITAL.

Introdução

Since it was declared a public health emergency of international concern, COVID-19 represents a danger to all people, however, certain subgroups seem particularly vulnerable to complications and death. In this context, oncology patients may present risk factors for COVID-19 infection and the evolution of the clinical picture in a severe way that may lead to death. Objectives: To evaluate the clinical characteristics, epidemiology and outcomes of cancer patients diagnosed with COVID-19 (ICU admission, hospital discharge or death).

Objetivo

To evaluate the clinical characteristics, epidemiology and outcomes of cancer patients diagnosed with COVID-19 (ICU admission, hospital discharge or death).

Método

The study was conducted in two reference hospitals for cancer care in São Luís, Maranhão. The sample population was individuals diagnosed with cancer and with covid-19 infection confirmed by RT-PCR of nasopharyngeal swab. The study was cross-sectional and retrospective. Data processing and analysis were carried out using Stata® software version 14.0.

Resultado

Ninety-six cancer patients with covid-19 infection were evaluated. The majority belonged to the male gender (52.1%). The predominant age group was people ≥ 60 years (57.3%). The most recurrent neoplasms were hematological (33.3%), female genital organs (20.8%) and gastrointestinal tract (14.6%). It was found that 61.5% had other diseases. Among them, the most frequent were systemic arterial hypertension (32.3%), diabetes mellitus II (11.5%), and heart diseases (8.3%). The most common symptoms related to covid-19 infection were dyspnea (53.1%), cough (49.0%), and fever (35.4%). As for complications, 67.7% had at least one. Among them were respiratory failure (55.8%), shock (12.5%), and renal failure (8.3%). As for ICU, 39.6% needed to be admitted in this sector, having as associated factors: living in the capital city (p=0.01), having cancer in the urinary tract (p=0.02), and having undergone surgery as the last treatment (p=0.01). As for death, a rate of 62.5% was found, with the following associated factors: male gender (p=0.04), living in the capital (p=0.01), having a spouse (p=0.04), having undergone surgery as the last treatment (p=0.04), and being in palliative care (p<0.05).

Conclusão

This study showed a high rate of deaths. Furthermore, we found associated factors commonly described as male gender and others infrequently described as having a spouse and surgery as the last treatment in other studies.

Palavras-chave

COVID-19, Neoplasms, death