Dados do Trabalho

Título

Evolution of cancer patients with confirmed diagnosis of covid 19 in a High Complexity Oncology Reference Center

Introdução

The new coronavirus was first thought to cause viral pneumonia and was discovered as a viral manifestation in the city of Wuhan, in December 2019, in China. Afterwards, it was discovered that it can cause the severe acute respiratory syndrome coronavirus 2 (SARS - COV - 2). This name is accepted worldwide for the disease that was originally called 2019 - nCoV. COVID 19 started as an isolated case in China and became a pandemic a few months later, in early 2020. It has flu-like symptoms such as fever, cough and shortness of breath and may be added to other manifestations such as diarrhea, fatigue, anosmia, dysgeusia, conjunctivitis, pharyngitis, fever and rash. Contagion is simple via air droplets during human-to-human contact. Diagnosis begins with clinical and epidemiological suspicion, and is confirmed through tests with antigens, antibodies or polymerase chain reaction (PCR). Immersed in this scenario, cancer patients are vulnerable to contagion and death, due to their inherent immunosuppression.

Objetivo

The prognosis of cancer patients who tested positive for COVID 19 and analyze the epidemiological profile of the primary outcomes among these patients.

Método

This is an observational, retrospective, cohort study with cancer patients diagnosed with SARS-CoV-2 infection or another respiratory virus diagnosed during the period from March 2020 to February 2021 at the Napoleão Laureano hospital. A p<0.05 and a 95% confidence interval were adopted, and its significance was verified with Pearson's chi-square test.

Resultado

The patients progressed to a worse primary outcome, requiring mechanical ventilation or death, or a good primary outcome, without the need for IMV and cure. Of the 94 patients positive for covid 19, 29 had a poor outcome. The lethality rate was 25.6% with 95% CI (16.7% - 34.3%). The age group influenced (p=0.01), so the elderly have a worse evolution. Hematologic cancer was the most common. There was a predominance of females (56.4%), living mainly in the urban area (80.9%).

Conclusão

It was noticed that covid - 19 generated more poor primary outcome with higher lethality and that this was higher in elderly patients over 60 years old. There was a prevalence in adults with covid 19 and death or need for intubation. Hematologic patients were more affected by covid 19.

Palavras-chave

covid 19; factor risk; cancer

Área

Oncologia - Pesquisa Clínica em Oncologia