Dados do Trabalho

Título

ORAL ANTINEOPLASTIC THERAPY: ANALYSIS OF ADHERENCE, SELF-EFFICACY AND ASSOCIATED FACTORS.

Introdução

Oral therapy is a valuable option for the treatment of cancer patients due to its ease of administration, minimal interruption of activities of daily living, as well as less need for hospitalization. With the use of oral medications, the patient becomes responsible for the management of their care and adherence becomes an important factor, as it can influence the effectiveness of the treatment.

Objetivo

To identify the rate of adherence to oral antineoplastic therapy and to analyze the factors associated with adherence to treatment.

Método

Cross-sectional study. The population consisted of cancer patients on oral antineoplastic therapy. The consecutive sample. The patients were evaluated using a sociodemographic and clinical form and the instruments Measurement of Treatment Adherence, the Brazilian version of the Adherence Determinants Questionnaire, the M.D. Anderson Symptom Inventory core and the Medication Adherence Self-Efficacy Scale.

Resultado

Participants were 127 patients on oral antineoplastic treatment. The average age was 56 years, with a predominance of females. The most frequent diagnosis was breast cancer, predominantly with a local tumor and zero ECOG. The intensity of symptoms was low and self-efficacy was high. The adherence rate was 97% and was associated with age, work situation and medication withdrawal time. There was no relationship between adherence and clinical variables. Adherence was positively and weakly correlated with the interpersonal aspects of care, intentions, intensity of symptoms in the last 24 hours and the interference of symptoms with life. Self-efficacy for taking medications in difficult circumstances and self-efficacy for medication adherence were weakly and positively correlated.

Conclusão

The rate of adherence to oral antineoplastic agents was high and showed a significant association with age, work situation and medication withdrawal time. There was no relationship between adherence and clinical variables. Adherence to oral antineoplastic agents was positively and weakly correlated with the interpersonal aspects of care, intentions, intensity of symptoms in the last 24 hours and the interference of symptoms with life. Self-efficacy for adherence to oral antineoplastic agents was high and presented a weak correlation with treatment adherence.

Palavras-chave

Medication adherence; Neoplasms; Self Efficacy.

Área

Oncologia - Enfermagem em oncologia clínica